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Masataka Adachi Selected Research

camostat

8/2021A serine protease inhibitor camostat mesilate prevents podocyte apoptosis and attenuates podocyte injury in metabolic syndrome model rats.
10/2016A serine protease inhibitor attenuates aldosterone-induced kidney injuries via the suppression of plasmin activity.
2/2016Combination therapy with renin-angiotensin-aldosterone system inhibitor telmisartan and serine protease inhibitor camostat mesilate provides further renoprotection in a rat chronic kidney disease model.
1/2015The serine protease inhibitor camostat mesilate attenuates the progression of chronic kidney disease through its antioxidant effects.
7/2013The antifibrotic effect of a serine protease inhibitor in the kidney.
1/2009Camostat mesilate inhibits prostasin activity and reduces blood pressure and renal injury in salt-sensitive hypertension.

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Masataka Adachi Research Topics

Disease

14Neoplasms (Cancer)
01/2019 - 11/2012
6Hypertension (High Blood Pressure)
11/2021 - 01/2005
6Ovarian Neoplasms (Ovarian Cancer)
09/2017 - 01/2014
5Infertility (Sterility)
11/2020 - 10/2017
5Fibrosis (Cirrhosis)
10/2016 - 10/2012
4Infections
09/2020 - 02/2016
4Reperfusion Injury
10/2018 - 09/2016
4Carcinogenesis
11/2017 - 01/2014
3Wounds and Injuries (Trauma)
08/2021 - 07/2006
3Endometrial Neoplasms (Endometrial Cancer)
09/2017 - 04/2015
3Breast Neoplasms (Breast Cancer)
03/2017 - 03/2015
3Hereditary Nonpolyposis Colorectal Neoplasms (Hereditary Nonpolyposis Colorectal Cancer)
03/2015 - 11/2014
2Proteinuria
08/2021 - 10/2012
2Anemia
02/2021 - 08/2004
2Chronic Kidney Failure (Chronic Renal Failure)
02/2021 - 10/2012
2Acute Kidney Injury (Acute Renal Failure)
12/2018 - 11/2018
2Ischemia
10/2017 - 09/2016
2Ureteral Obstruction
10/2016 - 07/2013
2Uterine Cervical Neoplasms (Cancer of the Cervix)
02/2016 - 09/2014
2Chronic Renal Insufficiency
02/2016 - 01/2015
2Insulin Resistance
03/2014 - 06/2011
1Metabolic Syndrome (Dysmetabolic Syndrome X)
08/2021
1Rodent Diseases
08/2021
1Lymphoproliferative Disorders (Lymphoproliferative Disorder)
11/2020
1Septic Shock (Toxic Shock Syndrome)
09/2020
1Ovarian Epithelial Carcinoma
06/2020
1Premature Aging
01/2020
1Adenomyoma
12/2019
1Polyps
12/2019
1Membranoproliferative Glomerulonephritis (Membranoproliferative Glomerulonephritis, Type II)
11/2019
1Lymphocele
01/2019
1Abscess
01/2019
1Body Weight (Weight, Body)
11/2018
1Leukemia
11/2017
1Carcinosarcoma
11/2017
1Sarcoma (Soft Tissue Sarcoma)
03/2017
1Fibrosarcoma
03/2017
1Carcinoma (Carcinomatosis)
03/2017
1Colorectal Neoplasms (Colorectal Cancer)
10/2016
1Kidney Diseases (Kidney Disease)
10/2016
1Clear Cell Adenocarcinoma
02/2016

Drug/Important Bio-Agent (IBA)

8Serine Proteinase Inhibitors (Serine Protease Inhibitors)IBA
08/2021 - 01/2003
7Pharmaceutical PreparationsIBA
09/2020 - 01/2014
7Proteins (Proteins, Gene)FDA Link
06/2020 - 02/2002
6SaltsIBA
11/2021 - 01/2005
6camostatIBA
08/2021 - 01/2009
4Biomarkers (Surrogate Marker)IBA
06/2020 - 01/2014
4prostasinIBA
03/2014 - 02/2002
3Serine Proteases (Serine Protease)IBA
08/2021 - 03/2014
3Anti-Bacterial Agents (Antibiotics)IBA
01/2019 - 07/2006
3AldosteroneIBA
10/2016 - 02/2002
3Messenger RNA (mRNA)IBA
01/2015 - 02/2002
2Cisplatin (Platino)FDA LinkGeneric
12/2018 - 11/2018
2ChromatinIBA
11/2017 - 09/2016
2AdenineFDA LinkGeneric
02/2016 - 01/2015
2Paclitaxel (Taxol)FDA LinkGeneric
04/2015 - 09/2014
2CollagenIBA
07/2013 - 10/2012
2Amiloride (Midamor)FDA LinkGeneric
08/2009 - 01/2005
2Uric Acid (Urate)IBA
04/2005 - 12/2003
2SodiumIBA
01/2005 - 01/2003
1continuous erythropoietin receptor activatorFDA Link
02/2021
1AntibodiesIBA
11/2020
1OligonucleotidesIBA
12/2019
1Antiviral Agents (Antivirals)IBA
11/2019
116S Ribosomal RNAIBA
01/2019
1Ribosomal DNA (rDNA)IBA
01/2019
1SirtuinsIBA
12/2018
1Doxycycline (Periostat)FDA LinkGeneric
11/2018
1Drinking WaterIBA
11/2018
1Tetracycline (Achromycin)FDA LinkGeneric
11/2018
1DNA HelicasesIBA
11/2017
1Sucrose (Saccharose)IBA
11/2017
1Carrier Proteins (Binding Protein)IBA
11/2017
1Fluconazole (Zonal)FDA LinkGeneric
10/2017
1Mevalonic Acid (Mevalonate)IBA
09/2017
1Lovastatin (Mevacor)FDA LinkGeneric
09/2017
1Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
09/2017
1geranylgeranyl pyrophosphate (geranylgeranyl diphosphate)IBA
09/2017
1farnesyl pyrophosphate (farnesyl diphosphate)IBA
09/2017
1Antineoplastic Agents (Antineoplastics)IBA
09/2017
1hydrogen sulfite (bisulfite)IBA
06/2017
1Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
03/2017
1TOR Serine-Threonine KinasesIBA
03/2017
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
03/2017
1Poly(ADP-ribose) Polymerase InhibitorsIBA
03/2017
1MutS ProteinsIBA
10/2016
1DNA (Deoxyribonucleic Acid)IBA
10/2016
1MutL Protein Homolog 1IBA
10/2016
1FibrinolysinFDA Link
10/2016
1temsirolimusFDA Link
02/2016
1Metformin (Glucophage)FDA LinkGeneric
02/2016

Therapy/Procedure

11Therapeutics
11/2019 - 07/2006
7Transplantation
11/2020 - 09/2016
3Renal Dialysis (Hemodialysis)
01/2020 - 08/2004
3Warm Ischemia
12/2017 - 09/2016
1Peritoneal Dialysis
02/2021
1Liver Transplantation
11/2019
1Radiotherapy
01/2019
1Lymph Node Excision (Lymph Node Dissection)
01/2019
1Operative Surgical Procedures
10/2018